Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IF
Concentration
1 mg/ml
Recomended Dilution
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR143. AA range:151-200
Subcellular Location
Melanosome membrane
Multi-pass membrane protein . Apical cell membrane
Multi-pass membrane protein . Distributed throughout the endo-melanosomal system but most of endogenous protein is localized in unpigmented stage II melanosomes. Its expression on the apical cell membrane is sensitive to tyrosine (PubMed:18828673). .
Multi-pass membrane protein . Lysosome membrane
Multi-pass membrane protein . Apical cell membrane
Multi-pass membrane protein . Distributed throughout the endo-melanosomal system but most of endogenous protein is localized in unpigmented stage II melanosomes. Its expression on the apical cell membrane is sensitive to tyrosine (PubMed:18828673). .
Multi-pass membrane protein . Lysosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
4935
Other Name
G-protein coupled receptor 143
GPR143
OA1
Ocular albinism type 1 protein
GPR143
OA1
Ocular albinism type 1 protein
Background
This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type