Información del producto
Trk C (phospho Tyr516) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Trk C around the phosphorylation site of Tyr516. AA range:482-531
Subcellular Location
Membrane
Single-pass type I membrane protein.
Single-pass type I membrane protein.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
4916
Observed Band
160kD
Other Name
GP145-TrkC
NT-3 growth factor receptor
NTRK3
Neurotrophic tyrosine kinase receptor type 3
TRKC
Trk-C
TrkC tyrosine kinase
NT-3 growth factor receptor
NTRK3
Neurotrophic tyrosine kinase receptor type 3
TRKC
Trk-C
TrkC tyrosine kinase
Background
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to