Trk A (phospho Tyr791) rabbit pAb
  • Trk A (phospho Tyr791) rabbit pAb
ELK

Trk A (phospho Tyr791) rabbit pAb

Ref: ELK-ES6423-50ul
50ul

Información del producto

Trk A (phospho Tyr791) rabbit pAb

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Información adicional
Storage Conditions -20°C/1 year
Applications ELISA
IF
IHC
Concentration 1 mg/ml
Recomended Dilution Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality Polyclonal
Immunogen The antiserum was produced against synthesized peptide derived from human Trk A around the phosphorylation site of Tyr791. AA range:747-796
Subcellular Location Cell membrane
Single-pass type I membrane protein . Early endosome membrane
Single-pass type I membrane protein . Late endosome membrane
Single-pass type I membrane protein . Rapidly internalized after NGF binding (PubMed:1281417). Internalized to endosomes upon binding of NGF or NTF3 and further transported to the cell body via a retrograde axonal transport. Localized at cell membrane and
Single-pass type I membrane protein . Recycling endosome membrane
Iso type IgG
Tissue Source Rabbit
Reactivity Human
Mouse
Rat
Human Gen 4914
Observed Band 140-180kD
Other Name High affinity nerve growth factor receptor
MTC
NTRK1
Neurotrophic tyrosine kinase receptor type 1
TRK
TRK1-transforming tyrosine kinase protein
TRKA
Tropomyosin-related kinase A
Tyrosine kinase receptor
Tyrosine kinase receptor A
Background This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to ce