Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human YB1 around the phosphorylation site of Ser102. AA range:68-117
Subcellular Location
Cytoplasm . Nucleus . Cytoplasmic granule . Secreted . Secreted, extracellular exosome . Predominantly cytoplasmic in proliferating cells (PubMed:12604611). Cytotoxic stress and DNA damage enhance translocation to the nucleus (PubMed:14718551). Localized
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
4904
Observed Band
36kD
Other Name
CBF-A
CCAAT-binding transcription factor I subunit A
DBPB
DNA-binding protein B
EFI-A
Enhancer factor I subunit A
NSEP1
Nuclease-sensitive element-binding protein 1
Y-box-binding protein 1
Y-box transcription factor
YB-
YB1
YBX1
Background
This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation