Información del producto
Cleaved-Notch 2 (A1734) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human NOTCH2. AA range:1715-1764
Subcellular Location
Single-pass type I membrane protein .
[Notch 2 extracellular truncation]: Cell membrane
[Notch 2 intracellular domain]: Nucleus . Cytoplasm . Following proteolytical processing NICD is translocated to the nucleus. Retained at the cytoplasm by TCIM (PubMed:25985737). .
[Notch 2 extracellular truncation]: Cell membrane
[Notch 2 intracellular domain]: Nucleus . Cytoplasm . Following proteolytical processing NICD is translocated to the nucleus. Retained at the cytoplasm by TCIM (PubMed:25985737). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
4853
Observed Band
110(cleaved)kD
Other Name
NOTCH2
Neurogenic locus notch homolog protein 2
Notch 2
hN2
Neurogenic locus notch homolog protein 2
Notch 2
hN2
Background
notch 2(NOTCH2) Homo sapiens This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF