Información del producto
IRP-1 (phospho Ser711) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human IREB1 around the phosphorylation site of Ser711. AA range:681-730
Subcellular Location
Cytoplasm, cytosol .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Rat
Monkey
Mouse
Rat
Human Gen
48
Observed Band
85kD
Other Name
ACO1
Aconitase
Citrate hydro-lyase
Cytoplasmic aconitate hydratase
Ferritin repressor protein
IRE-BP 1
IREB1
IRP1
Iron-responsive element-binding protein 1
Iron regulatory protein 1
Aconitase
Citrate hydro-lyase
Cytoplasmic aconitate hydratase
Ferritin repressor protein
IRE-BP 1
IREB1
IRP1
Iron-responsive element-binding protein 1
Iron regulatory protein 1
Background
The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4F