Información del producto
IκB-α (phospho Tyr305) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human IkappaB-alpha around the phosphorylation site of Tyr305. AA range:268-317
Subcellular Location
Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Rat
Monkey
Mouse
Rat
Human Gen
4792
Observed Band
about 40kd
Other Name
I-kappa-B-alpha
IKBA
IkB-alpha
IkappaBalpha
MAD3
Major histocompatibility complex enhancer-binding protein MAD3
NF-kappa-B inhibitor alpha
NFKBI
NFKBIA
IKBA
IkB-alpha
IkappaBalpha
MAD3
Major histocompatibility complex enhancer-binding protein MAD3
NF-kappa-B inhibitor alpha
NFKBI
NFKBIA
Background
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protei