Información del producto
NFATc1 (phospho Ser294) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human NFAT2 around the phosphorylation site of Ser294. AA range:261-310
Subcellular Location
Cytoplasm . Nucleus . Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustaine
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
4772
Other Name
NF-ATc
NF-ATc1
NFAT2
NFATC
NFATC1
NFATc
NFATc1
NFAT transcription complex cytosolic component
Nuclear factor of activated T-cells
cytoplasmic 1
NF-ATc1
NFAT2
NFATC
NFATC1
NFATc
NFATc1
NFAT transcription complex cytosolic component
Nuclear factor of activated T-cells
cytoplasmic 1
Background
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor