Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human MuSK (phospho Tyr755)
Subcellular Location
Cell junction, synapse, postsynaptic cell membrane
Single-pass type I membrane protein . Colocalizes with acetylcholine receptors (AChR) to the postsynaptic cell membrane of the neuromuscular junction. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
4593
Observed Band
97kD
Other Name
MUSK
MuSK
Muscle
Muscle-specific kinase receptor
Muscle-specific tyrosine-protein kinase receptor
skeletal receptor tyrosine-protein kinase
Background
This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myastheni