Información del producto
Mcl-1 (phospho Ser159) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MCL1 around the phosphorylation site of Ser159. AA range:125-174
Subcellular Location
Membrane
Single-pass membrane protein . Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Cytoplasmic, associated with mitochondria.
Single-pass membrane protein . Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Cytoplasmic, associated with mitochondria.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
4170
Observed Band
About 40kd in human,39kd in mouse and rat
Other Name
BCL2L3
Bcl-2-like protein 3
Bcl-2-related protein EAT/mcl1
Bcl2-L-3
Induced myeloid leukemia cell differentiation protein Mcl-1
MCL1
mcl1/EAT
Bcl-2-like protein 3
Bcl-2-related protein EAT/mcl1
Bcl2-L-3
Induced myeloid leukemia cell differentiation protein Mcl-1
MCL1
mcl1/EAT
Background
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively s