Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MARCKS around the phosphorylation site of Ser158. AA range:126-175
Subcellular Location
Cytoplasm, cytoskeleton . Membrane
Lipid-anchor .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
4082
Observed Band
35kD
Other Name
80 kDa protein, light chain
80K-L protein
MACS
MARCKS
MARCKS
Myristoylated alanine-rich C-kinase substrate
PKCSL
PRKCSL
Protein kinase C substrate
Background
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with