Información del producto
Lck (phospho Tyr505) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Lck around the phosphorylation site of Tyr505. AA range:460-509
Subcellular Location
Cell membrane
Cytoplasmic side . Cytoplasm, cytosol . Present in lipid rafts in an inactive form. .
Lipid-anchor
Cytoplasmic side . Cytoplasm, cytosol . Present in lipid rafts in an inactive form. .
Lipid-anchor
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
3932
Observed Band
56kD
Other Name
LCK
LSK
Leukocyte C-terminal Src kinase
Lymphocyte cell-specific protein-tyrosine kinase
Protein YT16
Proto-oncogene Lck
T cell-specific protein-tyrosine kinase
Tyrosine-protein kinase Lck
p56-LCK
LSK
Leukocyte C-terminal Src kinase
Lymphocyte cell-specific protein-tyrosine kinase
Protein YT16
Proto-oncogene Lck
T cell-specific protein-tyrosine kinase
Tyrosine-protein kinase Lck
p56-LCK
Background
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK doma