Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human RHOB. AA range:99-148
Subcellular Location
Late endosome membrane
Lipid-anchor. Cell membrane
Lipid-anchor. Nucleus. Cleavage furrow. Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus. Translocates to the equatorial region before furrow formation in a ECT2
Lipid-anchor. Cell membrane
Lipid-anchor. Nucleus. Cleavage furrow. Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus. Translocates to the equatorial region before furrow formation in a ECT2
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
388
Observed Band
22kD
Other Name
ARH6
ARHB
RHOB
Rho-related GTP-binding protein RhoB
Rho cDNA clone 6
h6
ARHB
RHOB
Rho-related GTP-binding protein RhoB
Rho cDNA clone 6
h6
Background
function:Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor for