Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from Cleaved-Kininogen-1 HC (K380) . at AA range: 300-380
Subcellular Location
Secreted, extracellular space.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
3827
Observed Band
41kD
Other Name
Alpha-2-thiol proteinase inhibitor
BDK
Fitzgerald factor
HMWK
High molecular weight kininogen
KNG
KNG1
Kininogen-1
Williams-Fitzgerald-Flaujeac factor
Background
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin