Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human KIT around the phosphorylation site of Tyr703. AA range:671-720
Subcellular Location
Single-pass type I membrane protein.
Single-pass type I membrane protein.
[Isoform 1]: Cell membrane
[Isoform 2]: Cell membrane
[Isoform 3]: Cytoplasm . Detected in the cytoplasm of spermatozoa, especially in the equatorial and subacrosomal region of the sperm head. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
3815
Observed Band
145kD
Other Name
CD antigen CD117
KIT
Mast/stem cell growth factor receptor Kit
PBT
Piebald trait protein
Proto-oncogene c-Kit
SCFR
SCFR
Tyrosine-protein kinase Kit
p145 c-kit
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Background
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as