Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human KCNK1. AA range:287-336
Subcellular Location
Cell membrane
Multi-pass membrane protein . Recycling endosome . Cell junction, synapse, synaptic cell membrane . Cytoplasmic vesicle . Perikaryon . Cell projection, dendrite . Cell projection . Apical cell membrane
Multi-pass membrane protein . The heterodimer with KCNK2 is detected at the astrocyte cell membrane. Not detected at the astrocyte cell membrane when KCNK2 is absent. Detected on neuronal cell bodies, and to a lesser degree on neuronal cell projections. D
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Rat
Human Gen
3775
Observed Band
38kD
Other Name
HOHO1
Inward rectifying potassium channel protein TWIK-1
KCNK1
KCNO1
Potassium channel KCNO1
Potassium channel subfamily K member 1
TWIK1
Background
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins fo