Información del producto
IP3R-I (phospho Ser1598) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Inositol 1,4,5-trisphosphate R1 around the phosphorylation site of Ser1598/1588. AA range:1566-1615
Subcellular Location
Endoplasmic reticulum membrane
Multi-pass membrane protein . Cytoplasm, perinuclear region . Endoplasmic reticulum and secretory granules (By similarity). .
Multi-pass membrane protein . Cytoplasmic vesicle, secretory vesicle membrane
Multi-pass membrane protein . Cytoplasm, perinuclear region . Endoplasmic reticulum and secretory granules (By similarity). .
Multi-pass membrane protein . Cytoplasmic vesicle, secretory vesicle membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
3708
Other Name
4,5-trisphosphate receptor type 1
INSP3R1
IP3 receptor isoform 1
IP3R 1
ITPR1
Inositol 1
InsP3R1
Type 1 InsP3 receptor
Type 1 inositol 1,4,5-trisphosphate receptor
INSP3R1
IP3 receptor isoform 1
IP3R 1
ITPR1
Inositol 1
InsP3R1
Type 1 InsP3 receptor
Type 1 inositol 1,4,5-trisphosphate receptor
Background
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type