Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ITK around the phosphorylation site of Tyr512. AA range:478-527
Subcellular Location
Cytoplasm . Nucleus . Localizes in the vicinity of cell surface receptors in the plasma membrane after receptor stimulation.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
3702
Observed Band
72kD
Other Name
EMT
IL-2-inducible T-cell kinase
ITK
Interleukin-2-inducible T-cell kinase
Kinase EMT
LYK
T-cell-specific kinase
Tyrosine-protein kinase ITK/TSK
Tyrosine-protein kinase Lyk
Background
This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by R