Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CD130/gp130. AA range:748-797
Subcellular Location
Single-pass type I membrane protein .
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
3572
Observed Band
160kD
Other Name
CD antigen CD130
CDw130
IL-6 receptor subunit beta
IL-6R-beta
IL-6RB
IL-6R subunit beta
IL6ST
Interleukin-6 receptor subunit beta
Interleukin-6 signal transducer
Membrane glycoprotein 130
Oncostatin-M receptor subunit alpha
gp130
Background
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine