Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the Internal region of human HLA-DPα1.
Subcellular Location
Cell membrane
Single-pass type I membrane protein. Endoplasmic reticulum membrane
Single-pass type I membrane protein. Endosome membrane
Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane
Single-pass type I membrane protein. Lysosome membrane
Single-pass type I membrane protein. The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation.
Single-pass type I membrane protein. Endoplasmic reticulum membrane
Single-pass type I membrane protein. Endosome membrane
Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane
Single-pass type I membrane protein. Lysosome membrane
Single-pass type I membrane protein. The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Human Gen
3113
Observed Band
29kD
Other Name
DP(W3)
DP(W4)
DP alpha 1 chain
HLA-DP1A
HLA-DPA1
HLA-SB alpha chain
HLASB
HLA class II histocompatibility antigen
MHC class II DP3-alpha
MHC class II DPA1
DP(W4)
DP alpha 1 chain
HLA-DP1A
HLA-DPA1
HLA-SB alpha chain
HLASB
HLA class II histocompatibility antigen
MHC class II DP3-alpha
MHC class II DPA1
Background
HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides de