Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human HCFC1. AA range:131-180
Subcellular Location
Cytoplasm . Nucleus . HCFC1R1 modulates its subcellular localization and overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm (PubMed:12235138). Non-processed HCFC1 associates with chromatin. Colocalizes with CREB3 and CANX in the ER.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
3054
Observed Band
208kD
Other Name
C1 factor
CFF
HCF
HCF-1
HCF1
HCFC1
HFC1
Host cell factor 1
VCAF
VP16 accessory protein
Background
This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleave
however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008],