Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Granzyme B. AA range:10-59
Subcellular Location
Secreted . Cytolytic granule . Delivered into the target cell by perforin (PubMed:20038786). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
2999
Observed Band
38kD
Other Name
C
C11
CGL1
CSPB
CTLA-1
CTLA1
CTSGL1
Cathepsin G-like 1
Cytotoxic T-lymphocyte proteinase 2
Fragmentin-2
GRB
GZMB
GZMH
Granzyme-2
Granzyme B
HLP
Human lymphocyte protein
Lymphocyte protease
SECT
T-cell serine protease 1-3E
Background
This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to g