Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human RAPGEF1. AA range:470-519
Subcellular Location
Early endosome .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2889
Other Name
CRK SH3-binding GNRP
GRF2
Guanine nucleotide-releasing factor 2
Protein C3G
RAPGEF1
Rap guanine nucleotide exchange factor 1
GRF2
Guanine nucleotide-releasing factor 2
Protein C3G
RAPGEF1
Rap guanine nucleotide exchange factor 1
Background
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-