Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TSEN54. AA range:261-310
Subcellular Location
Nucleus . Nucleus, nucleolus . May be transiently localized in the nucleolus. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
283989
Observed Band
60kD
Other Name
HsSEN54
SEN54
SEN54 homolog
TSEN54
tRNA-intron endonuclease Sen54
tRNA-splicing endonuclease subunit Sen54
SEN54
SEN54 homolog
TSEN54
tRNA-intron endonuclease Sen54
tRNA-splicing endonuclease subunit Sen54
Background
This gene encodes a subunit of the tRNA splicing endonuclease complex, which catalyzes the removal of introns from precursor tRNAs. The complex is also implicated in pre-mRNA 3-prime end processing. Mutations in this gene result in pontocerebellar hypopla