Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human KSR2. AA range:671-720
Subcellular Location
Cytoplasm . Membrane
Peripheral membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
283455
Observed Band
108kD
Other Name
KSR2
Kinase suppressor of Ras 2
hKSR2
Background
domain:The protein kinase domain is predicted to be catalytically inactive.,function:Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation