Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human GLRB. AA range:211-260
Subcellular Location
Cell junction, synapse, postsynaptic cell membrane
Multi-pass membrane protein . Cell junction, synapse . Cell projection, dendrite . Cell membrane
Multi-pass membrane protein . Cytoplasm . Retained in the cytoplasm upon heterologous expression by itself. Coexpression with GPHN promotes expression at the cell membrane (PubMed:12684523). Coexpression with GLRA1, GLRA2 or GLRA3 promotes expression at t
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
2743
Observed Band
56kD
Other Name
GLRB
Glycine receptor 58 kDa subunit
Glycine receptor subunit beta
Background
This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to