Información del producto
SPAK (phospho Ser309) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human STK39 around the phosphorylation site of Ser311. AA range:277-326
Subcellular Location
Cytoplasm . Nucleus . Nucleus when caspase-cleaved. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
27347
Observed Band
60kD
Other Name
DCHT
SPAK
STE20/SPS1-related proline-alanine-rich protein kinase
STK39
Serine/threonine-protein kinase 39
Ste-20-related kinase
SPAK
STE20/SPS1-related proline-alanine-rich protein kinase
STK39
Serine/threonine-protein kinase 39
Ste-20-related kinase
Background
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The cat