Información del producto
Pdcd-4 (phospho Ser67) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PDCD4 around the phosphorylation site of Ser67. AA range:33-82
Subcellular Location
Nucleus . Cytoplasm . Shuttles between the nucleus and cytoplasm (By similarity). Predominantly nuclear under normal growth conditions, and when phosphorylated at Ser-457 (PubMed:16357133). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Rat
Monkey
Mouse
Rat
Human Gen
27250
Observed Band
56kD
Other Name
H731
Neoplastic transformation inhibitor protein
Nuclear antigen H731-like
PDCD4
Programmed cell death protein 4
Protein 197/15a
Neoplastic transformation inhibitor protein
Nuclear antigen H731-like
PDCD4
Programmed cell death protein 4
Protein 197/15a
Background
This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, De