Información del producto
LAT (phospho Tyr191) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human LAT around the phosphorylation site of Tyr191. AA range:191-240
Subcellular Location
Cell membrane
Single-pass type III membrane protein . Present in lipid rafts.
Single-pass type III membrane protein . Present in lipid rafts.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
27040
Observed Band
28kD
Other Name
36 kDa phospho-tyrosine adapter protein
LAT
Linker for activation of T-cells family member 1
p36-38
pp36
LAT
Linker for activation of T-cells family member 1
p36-38
pp36
Background
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site