Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human GFR alpha-1. AA range:51-100
Subcellular Location
Cell membrane
Lipid-anchor, GPI-anchor . Golgi apparatus, trans-Golgi network . Endosome . Endosome, multivesicular body . Localizes mainly to the plasma membrane. In the presence of SORL1, shifts to vesicular structures, including trans-Golgi network, endosomes and mu
Lipid-anchor, GPI-anchor . Golgi apparatus, trans-Golgi network . Endosome . Endosome, multivesicular body . Localizes mainly to the plasma membrane. In the presence of SORL1, shifts to vesicular structures, including trans-Golgi network, endosomes and mu
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2674
Other Name
GDNFR-alpha-1
GDNFRA
GDNF family receptor alpha-1
GDNF receptor alpha-1
GFR-alpha-1
GFRA1
RETL1
RET ligand 1
TGF-beta-related neurotrophic factor receptor 1
TRNR1
GDNFRA
GDNF family receptor alpha-1
GDNF receptor alpha-1
GFR-alpha-1
GFRA1
RETL1
RET ligand 1
TGF-beta-related neurotrophic factor receptor 1
TRNR1
Background
This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) a