Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human GCHFR. AA range:31-80
Subcellular Location
Nucleus . Nucleus membrane . Cytoplasm, cytosol .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Rat
Human Gen
2644
Other Name
GCHFR
GFRP
GFRP
GTP cyclohydrolase 1 feedback regulatory protein
GTP cyclohydrolase I feedback regulatory protein
p35
Background
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine