Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human GBP1. AA range:71-120
Subcellular Location
Cytoplasm . Golgi apparatus membrane
Cytoplasmic side. Cell membrane . Secreted . Cytoplasmic vesicle . Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of IFNG induction. Golgi membrane localization requires isoprenylation and the presen
Lipid-anchor
Cytoplasmic side. Cell membrane . Secreted . Cytoplasmic vesicle . Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of IFNG induction. Golgi membrane localization requires isoprenylation and the presen
Lipid-anchor
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2633
Observed Band
68kD
Other Name
GBP-1
GBP1
GTP-binding protein 1
Guanine nucleotide-binding protein 1
HuGBP-1
Interferon-induced guanylate-binding protein 1
GBP1
GTP-binding protein 1
Guanine nucleotide-binding protein 1
HuGBP-1
Interferon-induced guanylate-binding protein 1
Background
Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence o