Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SENP3. AA range:10-59
Subcellular Location
Nucleus, nucleolus . Nucleus, nucleoplasm . Cytoplasm . Redistributes between the nucleolus and the nucleoplasm in response to mild oxidative stress (PubMed:19680224). Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chroma
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
26168
Observed Band
80kD
Other Name
SENP3
SSP3
SUMO-1-specific protease 3
SUSP3
Sentrin-specific protease 3
Sentrin/SUMO-specific protease SENP3
SSP3
SUMO-1-specific protease 3
SUSP3
Sentrin-specific protease 3
Sentrin/SUMO-specific protease SENP3
Background
MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have i
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1