Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human RNF19A. AA range:51-100
Subcellular Location
Membrane
Multi-pass membrane protein . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Present in the hyaline inclusion bodies specifically found in motor neurons from amyotrophic lateral sclerosis patients. Present in the Lewy bodies specific
Multi-pass membrane protein . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Present in the hyaline inclusion bodies specifically found in motor neurons from amyotrophic lateral sclerosis patients. Present in the Lewy bodies specific
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
25897
Observed Band
90kD
Other Name
Dorfin
Double ring-finger protein
E3 ubiquitin-protein ligase RNF19A
RING finger protein 19A
RNF19
RNF19A
p38
Double ring-finger protein
E3 ubiquitin-protein ligase RNF19A
RING finger protein 19A
RNF19
RNF19A
p38
Background
This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ub