Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ALPL. AA range:201-250
Subcellular Location
Cell membrane
Lipid-anchor, GPI-anchor . Extracellular vesicle membrane
Lipid-anchor, GPI-anchor . Mitochondrion intermembrane space . Localizes to special class of extracellular vesicles, named matrix vesicles (MVs), which are released by osteogenic cells. Localizes to the mitochondria of thermogenic fat cells: tethered to m
Lipid-anchor, GPI-anchor . Mitochondrion membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
249
Observed Band
70kD
Other Name
ALPL
AP-TNAP
Alkaline phosphatase
Alkaline phosphatase liver/bone/kidney isozyme
TNSALP
tissue-nonspecific isozyme
Background
This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located