Información del producto
mTOR (phospho Ser2481) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. ,WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human mTOR around the phosphorylation site of Ser2481. AA range:2447-2496
Subcellular Location
Cytoplasmic side . Golgi apparatus membrane
Cytoplasmic side . Lysosome . Cytoplasm . Nucleus, PML body . Microsome membrane . Lysosome membrane . Cytoplasmic vesicle, phagosome . Shuttles between cytoplasm and nucleus. Accumulates in the nucleus in response to hypoxia (By similarity). Targeting to
Cytoplasmic side . Mitochondrion outer membrane
Endoplasmic reticulum membrane
Peripheral membrane protein
Peripheral membrane protein
Peripheral membrane protein
Cytoplasmic side . Lysosome . Cytoplasm . Nucleus, PML body . Microsome membrane . Lysosome membrane . Cytoplasmic vesicle, phagosome . Shuttles between cytoplasm and nucleus. Accumulates in the nucleus in response to hypoxia (By similarity). Targeting to
Cytoplasmic side . Mitochondrion outer membrane
Endoplasmic reticulum membrane
Peripheral membrane protein
Peripheral membrane protein
Peripheral membrane protein
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Bovine
Human
Mouse
Rat
Human
Mouse
Rat
Human Gen
2475
Other Name
FK506-binding protein 12-rapamycin complex-associated protein 1
FKBP12-rapamycin complex-associated protein
FRAP
FRAP1
FRAP2
MTOR
Mammalian target of rapamycin
Mechanistic tar
RAFT1
RAPT1
Serine/threonine-protein kinase mTOR
mTOR
FKBP12-rapamycin complex-associated protein
FRAP
FRAP1
FRAP2
MTOR
Mammalian target of rapamycin
Mechanistic tar
RAFT1
RAPT1
Serine/threonine-protein kinase mTOR
mTOR
Background
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arres