Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PIK3R5. AA range:695-744
Subcellular Location
Nucleus . Cytoplasm . Cell membrane
Peripheral membrane protein . Predominantly localized in the nucleus in absence of PIK3CG/p120. Colocalizes with PIK3CG/p120 in the cytoplasm. Translocated to the plasma membrane in a beta-gamma G protein-dependent manner. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
23533
Observed Band
100kD
Other Name
5-bisphosphate 3-kinase regulatory subunit
PI3-kinase p101 subunit
PI3-kinase regulatory subunit 5
PIK3R5
Phosphatidylinositol 4
Phosphoinositide 3-kinase regulatory subunit 5
Protein FOAP-2
PtdIns-
PtdIns-3-kinase regulatory subunit
Background
Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks ar