Storage Conditions
-20°C/1 year
Applications
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498
Subcellular Location
Cytoplasm . Membrane . Translocated to the membrane upon stimulation. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
23365
Observed Band
173kD
Other Name
ARHGEF12
KIAA0382
LARG
Leukemia-associated RhoGEF
Rho guanine nucleotide exchange factor 12
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This pr