Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human FLT3. AA range:565-614
Subcellular Location
Membrane
Single-pass type I membrane protein. Endoplasmic reticulum lumen. Constitutively activated mutant forms with internal tandem duplications are less efficiently transported to the cell surface and a significant proportion is retained in an immature form in
Single-pass type I membrane protein. Endoplasmic reticulum lumen. Constitutively activated mutant forms with internal tandem duplications are less efficiently transported to the cell surface and a significant proportion is retained in an immature form in
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2322
Observed Band
117kD
Other Name
CD135
CD antigen CD135
FLK-2
FLK2
FLT-3
FLT3
FL cytokine receptor
Fetal liver kinase-2
Fms-like tyrosine kinase 3
Receptor-type tyrosine-protein kinase FLT3
STK-1
STK1
Stem cell tyrosine kinase 1
CD antigen CD135
FLK-2
FLK2
FLT-3
FLT3
FL cytokine receptor
Fetal liver kinase-2
Fms-like tyrosine kinase 3
Receptor-type tyrosine-protein kinase FLT3
STK-1
STK1
Stem cell tyrosine kinase 1
Background
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane le