Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ATG4B. AA range:71-120
Subcellular Location
Cytoplasm . Cytoplasm, cytosol . Cytoplasmic vesicle, autophagosome . Endoplasmic reticulum . Mitochondrion . Mainly localizes to the cytoplasm, including cytosol (PubMed:29165041). A samll potion localizes to mitochondria
phosphorylation at Ser-34 promotes localization to mitochondria (PubMed:29165041). .
phosphorylation at Ser-34 promotes localization to mitochondria (PubMed:29165041). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
23192
Observed Band
44kD
Other Name
APG4B
ATG4B
AUT-like 1 cysteine endopeptidase
AUTL1
Autophagin-1
Autophagy-related cysteine endopeptidase 1
Autophagy-related protein 4 homolog B
Cysteine protease ATG4B
KIAA0943
hAPG4B
ATG4B
AUT-like 1 cysteine endopeptidase
AUTL1
Autophagin-1
Autophagy-related cysteine endopeptidase 1
Autophagy-related protein 4 homolog B
Cysteine protease ATG4B
KIAA0943
hAPG4B
Background
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, a