Storage Conditions
-20°C/1 year
Applications
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SHANK2. AA range:331-380
Subcellular Location
Apical cell membrane . Cytoplasm . Cell junction, synapse . Cell junction, synapse, postsynaptic density . Cell projection, growth cone . Cell projection, dendritic spine . Colocalizes with cortactin in growth cones in differentiating hippocampal neurons.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
22941
Observed Band
135kD
Other Name
CORTBP1
CortBP1
Cortactin-binding protein 1
KIAA1022
Proline-rich synapse-associated protein 1
SH3 and multiple ankyrin repeat domains protein 2
SHANK2
Shank2
Background
This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density of excitatory synapses. Shank proteins contain multiple domains for protein-protein interaction, inc