Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human FGFR3. AA range:131-180
Subcellular Location
Single-pass type I membrane protein .
Single-pass type I membrane protein .
Single-pass type I membrane protein. Cytoplasmic vesicle. Endoplasmic reticulum. The activated receptor is rapidly internalized and degraded. Detected in intracellular vesicles after internalization of the autophosphorylated receptor.
[Isoform 1]: Cell membrane
[Isoform 2]: Cell membrane
[Isoform 3]: Secreted.
[Isoform 4]: Cell membrane
Single-pass type I membrane protein .
Single-pass type I membrane protein. Cytoplasmic vesicle. Endoplasmic reticulum. The activated receptor is rapidly internalized and degraded. Detected in intracellular vesicles after internalization of the autophosphorylated receptor.
[Isoform 1]: Cell membrane
[Isoform 2]: Cell membrane
[Isoform 3]: Secreted.
[Isoform 4]: Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2261
Observed Band
95-130kD
Other Name
CD antigen CD333
FGFR-3
FGFR3
Fibroblast growth factor receptor 3
JTK4
FGFR-3
FGFR3
Fibroblast growth factor receptor 3
JTK4
Background
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and