Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human FAP-1. AA range:331-380
Subcellular Location
Single-pass type II membrane protein . Cell projection, invadopodium membrane
Single-pass type II membrane protein . Cell projection, lamellipodium membrane
Single-pass type II membrane protein . Cell projection, ruffle membrane
Single-pass type II membrane protein . Localized on cell surface with lamellipodia and invadopodia membranes and on shed vesicles. Colocalized with DPP4 at invadopodia and lamellipodia membranes of migratory activated endothelial cells in collagenous matr
Single-pass type II membrane protein . Membrane
[Prolyl endopeptidase FAP]: Cell surface . Cell membrane
Single-pass type II membrane protein . Cell projection, lamellipodium membrane
Single-pass type II membrane protein . Cell projection, ruffle membrane
Single-pass type II membrane protein . Localized on cell surface with lamellipodia and invadopodia membranes and on shed vesicles. Colocalized with DPP4 at invadopodia and lamellipodia membranes of migratory activated endothelial cells in collagenous matr
Single-pass type II membrane protein . Membrane
[Prolyl endopeptidase FAP]: Cell surface . Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2191
Observed Band
90kD
Other Name
170 kDa melanoma membrane-bound gelatinase
FAP
Fibroblast activation protein alpha
Integral membrane serine protease
Seprase
FAP
Fibroblast activation protein alpha
Integral membrane serine protease
Seprase
Background
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant