Información del producto
PIP5KIII (phospho Ser307) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PIP5K around the phosphorylation site of Ser307. AA range:273-322
Subcellular Location
Endosome membrane
Peripheral membrane protein. Cytoplasmic vesicle, phagosome membrane
Peripheral membrane protein . Early endosome membrane
Peripheral membrane protein . Late endosome membrane
Peripheral membrane protein . Mainly associated with membranes of the late endocytic pathway. .
Peripheral membrane protein. Cytoplasmic vesicle, phagosome membrane
Peripheral membrane protein . Early endosome membrane
Peripheral membrane protein . Late endosome membrane
Peripheral membrane protein . Mainly associated with membranes of the late endocytic pathway. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
200576
Other Name
1-phosphatidylinositol 3-phosphate 5-kinase
FYVE finger-containing phosphoinositide kinase
KIAA0981
PIKFYVE
PIKfyve
PIP5K3
PIPkin-III
Phosphatidylinositol 3-phosphate 5-kinase
Phosphatidylinositol 3-phosphate 5-kinase type III
Type
FYVE finger-containing phosphoinositide kinase
KIAA0981
PIKFYVE
PIKfyve
PIP5K3
PIPkin-III
Phosphatidylinositol 3-phosphate 5-kinase
Phosphatidylinositol 3-phosphate 5-kinase type III
Type
Background
Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by
also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. The D-5 position also can be phosphory
also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. The D-5 position also can be phosphory