Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human APLF. AA range:82-131
Subcellular Location
Nucleus . Chromosome . Cytoplasm, cytosol . Localizes to DNA damage sites (PubMed:18474613, PubMed:18172500, PubMed:21211721, PubMed:23689425). Accumulates at single-strand breaks and double-strand breaks via the PBZ-type zinc fingers (PubMed:18172500). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
200558
Observed Band
57kD
Other Name
APLF
Aprataxin and PNK-like factor
Apurinic-apyrimidinic endonuclease APLF
C2orf13
PALF
PNK and APTX-like FHA domain-containing protein
XIP1
XRCC1-interacting protein 1
Aprataxin and PNK-like factor
Apurinic-apyrimidinic endonuclease APLF
C2orf13
PALF
PNK and APTX-like FHA domain-containing protein
XIP1
XRCC1-interacting protein 1
Background
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]).[supplied by OMIM, Mar 2008],