Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Aggrecan. AA range:320-369
Subcellular Location
Secreted, extracellular space, extracellular matrix .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Rat
Human Gen
176
Observed Band
44kD
Other Name
ACAN
AGC1
Aggrecan core protein
CSPCP
CSPG1
Cartilage-specific proteoglycan core protein
Chondroitin sulfate proteoglycan 1
Chondroitin sulfate proteoglycan core protein 1
MSK16
Background
This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal