Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Dyskerin. AA range:171-220
Subcellular Location
[Isoform 1]: Nucleus, nucleolus . Nucleus, Cajal body . Also localized to Cajal bodies (coiled bodies). .
[Isoform 3]: Cytoplasm .
[Isoform 3]: Cytoplasm .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1736
Observed Band
57kD
Other Name
CBF5 homolog
DKC1
Dyskerin
H/ACA ribonucleoprotein complex subunit 4
NOLA4
Nopp140-associated protein of 57 kDa
Nucleolar protein NAP57
Nucleolar protein family A member 4
snoRNP protein DKC1
DKC1
Dyskerin
H/ACA ribonucleoprotein complex subunit 4
NOLA4
Nopp140-associated protein of 57 kDa
Nucleolar protein NAP57
Nucleolar protein family A member 4
snoRNP protein DKC1
Background
dyskerin pseudouridine synthase 1(DKC1) Homo sapiens This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stabili