Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human DBH. AA range:401-450
Subcellular Location
Cytoplasmic vesicle, secretory vesicle membrane
Single-pass type II membrane protein .
Single-pass type II membrane protein . Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane
[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen . Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen . Secreted .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1621
Observed Band
69kD
Other Name
DBH
Dopamine beta-hydroxylase
Dopamine beta-monooxygenase
Background
The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exist