Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human C14orf49. AA range:169-218
Subcellular Location
Nucleus outer membrane
Single-pass type IV membrane protein . Nucleus envelope . Rough endoplasmic reticulum .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
161176
Observed Band
115kD
Other Name
C14orf49
Nesprin-3
Nuclear envelope spectrin repeat protein 3
SYNE3
Background
function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system.,similarity: