Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 1A2. AA range:331-380
Subcellular Location
Endoplasmic reticulum membrane
Peripheral membrane protein.
Peripheral membrane protein. Microsome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1544
Other Name
CYP1A2
CYPIA2
Cytochrome P(3)450
Cytochrome P450 1A2
Cytochrome P450 4
Cytochrome P450-P3
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encode
however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats i